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Treatment Of Genitourinary Syndrome of Menopause (Vaginal Atrophy) Using MonaLisa Touch

MonaLisa Touch is a non-surgical, non-hormonal alternative for the treatment of Genitourinary Syndrome of Menopause (GSM) or Vaginal Atrophy.


This revolutionary treatment is quick, comfortable for patients, requires no downtime and provides your patients with relief for up to 12 – 18 months. These symptoms can include dyspareunia, vaginal itching, burning, dryness, and their resultant impacts on quality of life.

The treatment can be used in conjunction with Hormone Therapy, as an alternative treatment for patients who are not suitable for Hormone Therapy, or for those patients who have found Hormone Therapy to be ineffective.

MonaLisa Touch works by stimulating the body’s regenerative processes to create more hydrated and healthy cells, and to improve the vascularity of the vaginal mucosa. This improves the integrity and elasticity of the vaginal wall and normalises pH (increases the acidity) of the vaginal environment. MonaLisa Touch improves the health and function of the vagina.

MonaLisa Touch was introduced into Australia in January 2013 and more than 10,000 treatments have been performed. The feedback from the Australian doctors performing the treatments is that MonaLisa Touch is consistently exceeding their expectations. And for many of the patients who have experienced the MonaLisa Touch procedure it has been life-changing.

Most patients experience a noticeable improvement after just one MonaLisa Touch treatment, however a course of three treatments one month apart is recommended. Patients can return to their normal daily activities immediately following a MonaLisa Touch procedure with the only post-treatment instruction being no sexual activity for five days.

Order your client information brochures

You can download our patient brochure here or if you would prefer that we send you printed brochures, please let us know how many you need?

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The Only Treatment Against Vaginal Atrophy Symptoms Supported by Clinical Studies

Vaginal atrophy is a very common condition, especially among women in menopause (either natural or induced) or during post-partum. The vulvovaginal region is very sensitive to estrogen decline, with a series of consequences that impact directly on the quality of a woman’s life: weakness and laxity of the vaginal mucosa, dryness, itching and burning, pain during sexual intercourse (dyspareunia).

MonaLisa Touch ® is the only procedure proven not only by clinical results but also by detailed ultrastructural and histological studies. Scientific publications of the results demonstrate the effective tissue regeneration achieved thanks to the unique combination of the wavelength of the CO2 laser, the structure of the D-Pulse and adequate emission power.

With MonaLisa Touch ® comes a method, with a unique concept, for restoring the trophic conditions of the vulvovaginal region.

During menopause, the mucosa presents a particular condition with metabolically quiescent fibrocytes as opposed to fibroblasts, unable to actively produce collagen, hyaluronic acid and other molecules needed for an adequate glycoprotein ground matrix. This can result in dry mucosa because it is dehydrated and less well nourished meaning it is fragile and more prone to infections.

A Scientific Analysis of A New Laser Technique Against Vaginal Atrophy

What's happens to vaginal mucosa during MonaLisa Touch CO2 laser treatment? Prof. Alberto Calligaro explains how laser acts on epithelium and connective tissue and how mucosa rejuvenates. (3.16 mins)

MonaLisa Touch-The New Laser Treatment Against Vaginal Atrophy, Laxity and Urinary Incontinence

MonaLisa Touch simply acts on the mucosa stimulating biosynthesis of new collagen and tissue regeneration process. The procedure is fast, simple, safe and painless thanks to the 360° laser treatment in one time! (3.37 mins)

MonaLisa Touch® – The New Laser Against Vaginal Atrophy, Laxity and Urinary Incontinence

With low water content in the connective tissue, both nutrients and lymphocyte defenses, which get to the lamina propria via the blood vessels, find it harder to migrate through the connective tissue matrix to reach the epithelium. Without nourishment, the epithelium thins, which reduces the shedding of superficial cells, resulting in decreased glycogen in the vaginal lumen. Numbers of lactobacilli, which feed on glycogen and serve to maintain proper acidity in the vaginal environment, are therefore reduced. The pH thus increases, favoring attacks by pathogenic bacteria and the onset of infections.

So the purpose of treating vaginal atrophy is to promote and recover pre-menopausal metabolic activity by means of a new synthesis not only of collagen, but also of hyaluronic acid, glycosaminoglycans and proteoglycans. This helps to regain hydrated mucosa that in turn restores a proper trophic supply to the tissues, thus reinstating all the functions typical of younger healthy tissue.

This is the stimulatory effect produced by the MonaLisa Touch®, treatment, whose laser action induces functional rejuvenation of the vaginal mucosa!

Testimonials from patients (DEKA Laser)

3 women (2 of them breast cancer survivors) talk about their experience and reveals how the most intimate discomforts from atrophic vaginitis can be solved by MonaLisa Touch® vaginal treatment by DEKA. (2.40 mins)

Testimonials from patients in Australia

An interview with an australian woman who underwent a MonaLisa Touch treatment and Dr Fariba Behnia-Willison explained the real benefits of this revolutionary treatment.

Other Applications

The non pharmacological therapy for vaginal laxity (tightening)

Laxity of the vagina and introitus can occur from vaginal delivery or to be part of natural ageing process. Vaginal laxity may be a bothersome condition to patients that may impact on “happiness and sexual function”.


Thanks to the effective action of the D-Pulse, MonaLisa Touch® improves and replaces also the most common techniques for treating vaginal relaxation due to a loss of tone of vaginal mucosa.


When inserted in the vagina by using the special probe of the HiScan V2LR scanning system, the laser acts directly on the mucosa of the walls, tightening, reshaping, toning and stimulating tissue and regenerating collagen.

The non surgical treatment of mild urinary incontinence

Recent studies show that MonaLisa Touch® is largely effective in treating one of the most embarrassing symptom that seriously affects many women after childbirth or in menopause: mild urinary incontinence.


The beneficial stimulation of vaginal tissues, due to the D-Pulse CO2 laser emission, re-establish the proper functionality of urogenital involved structures.


This allows restoration of correct urinary continence, with a dramatic positive improvement in the quality of life, both physically and psychologically.

The missing solution to postpartum intimate problems

Postpartum sexuality is an important aspect of women’s health.


Many women commonly experience postpartum sexual problems such as dyspareunia due to lactational atrophic vaginitis or following perineal trauma.


Consequently, painful sexual intercourse is the most common sexual problem for puerperae and represents both a physical and psychological problem for many women and their partners.


In these situations, an early and sensitive management is crucial in preventing long-term problems.

Today, thanks to the capabilities of MonaLisa Touch® to stimulate tissue regeneration, it is now possible to resolve these situations delicately and safely.
The treatment acts gently by stimulating collagen production, improving the functionality of the treated area and restoring the proper trophic balance of the mucous membranes.

Register your interest in attending or hosting a MonaLisa Touch workshop

Clinic 66 is planning to host a series of events to introduce this ground breaking new treatment option to local Specialists and General Practitioners. If you would like to be invited or if you have a group of doctors that would like to learn more in your practice, please let us know and we'll be in touch soon.

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Want to know more about the science?

Browse the scientific articles on MonaLisa Touch® that have been published in prestigious international journals. Read the white papers: detailed reports resulting from the direct experience of doctors who already use the machine. Compare histologies of the vaginal mucosa BEFORE and AFTER treatment. Access a broad insight into the treatment: from laser physics to the effects of laser interaction on the vaginal mucosa. Registration is required to access this content from MonaLisa Touch and DEKA.

Testimonials from Doctors

Mickey Karram MD, Christ Hospital, USA

“A game changer. I like to use this word because it is fulfilling a huge void for women. Vaginal Atrophy is a huge problem: millions and millions of women are suffering from this, and unfortunately most of them are suffering in silence. A big group of them is composed by young women who can’t even take the medicines, are the breast cancer survivors. MonaLisa® is a very needed therapy for medicine”

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